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ZINC FINGER E-BOX-BINDING HOMEOBOX 1
Descriptors Found:
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DeCS
Descriptor
English
:
Zinc Finger E-box-Binding Homeobox 1
Descriptor
Spanish
:
Homeobox 1 de Unión a la E-Box con Dedos de Zinc
Descriptor
Portuguese
:
Homeobox 1 de Ligação a E-box em Dedo de Zinco
Synonyms
English
:
NIL-2-A Zinc Finger Protein
TCF8 Protein
Transcription Factor 8
Zeb1 Transcription Factor
NIL 2 A Zinc Finger Protein
Transcription Factor, Zeb1
Zinc Finger E box Binding Homeobox 1
Tree Number:
D12.776.260.400.906
D12.776.260.703.800
D12.776.930.780.945
Definition
English
:
A transcription factor characterized by N-terminal and C-terminal
CYS2-HIS2 ZINC FINGERS
separated by a homeobox. It represses the expression of E-CADHERIN to induce the
EPITHELIAL-MESENCHYMAL TRANSITION
. It also represses
PROTO-ONCOGENE PROTEINS C-BCL-6
; regulates the cell type-specific expression of
SODIUM-POTASSIUM-EXCHANGING ATPASE
; and promotes neuronal differentiation.
History Note
English
:
2017
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
56604
Unique Identifier:
D000071799
Occurrence in VHL
:
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CID-10
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